When kidneys fail, the only treatment options available are either transplant or dialysis, with dialysis being the most common. There are Currently, 15,000 Australians are on dialysis, but remarkably, the AIHW estimates 50% of new cases of renal failure each year (3300) Australians will choose end-of-life care over dialysis, such is the loss in quality of life associated with this treatment. Clearly, today's gold standard of care is failing our patients. Globally, there are over 3 million people on dialysis, though it's estimated that 7-9 million people need treatment but cannot access it due to a lack of affordability. Over the last 20 years, renal disease has risen to the 9th leading cause of death worldwide, up from 19th place in the year 2000 (WHO, 2020), and is estimated to be the 5th leading cause of death by 2040 (Kovesdy, 2022).